Found 157 matching trials
T Cell Receptor Immunotherapy Targeting MAGE-A3 for Patients With Metastatic Cancer Who Are HLA-DP0401 Positive
PHASE1Background:
The National Cancer Institute (NCI) Surgery Branch has develop...
Location
National Institutes of Health Clinical Center, 9000 Rockville Pike
Gene-Modified White Blood Cells Followed By Interleukin-2 and Vaccine Therapy in Treating Patients With Metastatic Melanoma
PHASE1RATIONALE: Inserting a gene that has been created in the laboratory into a ...
Location
Warren Grant Magnuson Clinical Center - NCI Clinical Trials Referral Office
PD-1 Knockout Engineered T Cells for Metastatic Non-small Cell Lung Cancer
PHASE1This study will evaluate the safety of PD-1 knockout engineered T cells in ...
Location
West China Hospital, Sichuan University
Rituximab, Fludarabine, and Cyclophosphamide or Observation Alone in Treating Patients With Stage 0, Stage I, or Stage II Chronic Lymphocytic Leukemia
PHASE3RATIONALE: Monoclonal antibodies, such as rituximab, can block cancer growt...
Location
Universitaetsklinik fuer Innere Medizin I
Gene-Modified T Cells With or Without Decitabine in Treating Patients With Advanced Malignancies Expressing NY-ESO-1
PHASE1This phase I/IIa trial studies the side effects and best dose of gene-modif...
Status
Active Not Recruiting
Location
Roswell Park Cancer Institute
Interleukin-12 and Interferon Alfa in Treating Patients With Metastatic Malignant Melanoma
PHASE2Phase II trial to study the effectiveness of combining interleukin-12 and i...
Location
Cancer and Leukemia Group B
Melanocortin Gene Expression in Lymphocytes of Polymyalgia Patients
N/APolymyalgia rheumatica (PMR) is a systemic inflammatory disorder with unkno...
Location
Multiple Locations
A Study of BCMA-directed CAR-T Cells Treatment in Subjects With r/r Multiple Myeloma
PHASE1This is a single-center, non-randomized study to evaluate the safety and ef...
Location
Peking Union Medical College Hospital
Intermediate-size IND for Treatment of KRAS G12V-mutant Tumors
N/AThis intermediate-size IND will treat participants with incurable, advanced...
Status
Temporarily Not Available
Location
Multiple Locations
A Phase 1/2 Study of Intravenous Gene Transfer With an AAV9 Vector Expressing Human Beta-galactosidase in Type I and Type II GM1 Gangliosidosis
PHASE1Background:
GM1 gangliosidosis is a disorder that destroys nerve cells. It...
Location
National Institutes of Health Clinical Center